VLPs (virus like particle) is usually composed of one or more viral structural proteins. The spatial structure of the virus is similar to that of a real virus, but it cannot replicate itself due to the lack of genetic material. VLP has the characteristics of being an exogenous antigen and has great potential in vaccine production. The preparation of virus like particles VLPs is usually undertaking in the expression system and then assembled in vitro. Insect cell expression system is the most commonly used expression system in the preparation of VLPs.
As the number of the VLP's subunits may vary and multi gene insertion is not as easy, Creative BioMart provides two VLP expression strategies that suitable for VLP with 4 or less subunits. As an expert in biotechnology, Creative BioMart promises to provide high quality service to our customers and we will always be your reliable partner.
Suitable for 1 to 2 subunits insertion. Donor with two MCS site is adopted here. The subunits will be expressed as normal foreign according to the working principle of Bac to Bac expression approach.
If the number of gene cassettes is over 2 but not as much as 4, we will either construct a multi gene vector via a kind of vector which has the max capacity of 4 genes or inset the single subunit sequence into transfer vector and carry out co-transfection.
The technology platform on which VLP expression based had been well-developed in Creative BioMart.
Expression success rate is over 95% at Creative BioMart. Our mature technology platform promises to save your money and time.
It takes only 7 weeks on average from gene synthesis to large-scale expression
Just provide the sequence of the target protein and we will solve the rest of problem for you.
Creative BioMart has more than 10 years of experience in protein expression and is competent to satisfy various protein expression desire. We are expert in protein expression (intracellular or secretory), signal peptide selection, insect cell selection and culture. Choosing our expression service, customers only need to provide the coding sequence of your target protein. We will provide customizes service from codon optimization to large-scale expression and purification. For more assistance, please contact us for help.